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Estrace is a female sex hormone which is produced by ovaries. It is necessary for many activities in the body which mainly includes menopause and osteoporosis. The symptoms of menopause include hot flashes, vaginal dryness, burning and irritation. 

Estrace is used as replacement therapy to relieve from symptoms of menopause. Estrace is also indicated in case of post-menopausal women who might have incidence of fractures due to estrogen deficiency. Estradiol is prescribed for breast cancer and in some case of prostate cancer.

Quantity Strength Price Unit Price
28 Tablets Estrace 1mg $29.99 $1.07
84 Tablets Estrace 1mg $84.99 $1.01
28 Tablets Estrace 2mg $31.99 $1.14
84 Tablets Estrace 2mg $95.99 $1.14


Estrace has an active constituent called as estradiol which is more precisely called 17beta- estradiol. Estradiol is important for the maintenance of menstrual reproductive cycle. Estradiol is produced in the endocrine tissues such as follicle ovaries of female and non-endocrine tissue such as liver, breast and neural tissue. In osteoporosis estradiol has profound effect on bone which is observed in women post menopause where accelerated loss of bone mass is reported due to estrogen deficiency.

Additional Information

Generic ESTRADIOL (ess-tra-DYE-ole)
Strength Estrace - ESTRADIOL 1mg, 2mg

The strength of Estrace tablets available is from 1mg to 2mg and the dosage of is used for many medical conditions. In case of vaginal atrophy associated with menopause the initial dose is from 1mg to 2mg daily. Administration should be cyclic that is three weeks on and one week off. In case of hypogonadism initial dose is of 1 to 2 mg daily of estradiol. In case of breast cancer the dose is 10 mg three times daily at least for three months. In advanced androgen-dependent carcinoma dose is 1 to 2mg three times daily. The missed dose needs to be taken as soon as you remember .Skip the missed dose in case it’s time for the next dose. No extra medication is required to make up the missed dose. In case of overdose nausea, vomiting and vaginal bleeding is observed. The patient should seek immediate medical attention by calling the doctor.

Side Effects

Different side effects ranging from mild to severe are observed with Estrace. The severe side effects seen are unusual vaginal bleeding, nausea, vomiting, lump formation in the breast, severe headache, pain, swelling and tenderness, confusion, problems with vision, speech or balance, feeling of tiredness, chest pain, rapid breathing and fast hear beat. In such cases the doctor needs to be consulted immediately. The common side effects or less serious in nature are mild nausea, loss of scalp hair, darkening of facial skin, vaginal itching or discharge and changes in menstrual periods.


Increase in the blood pressure has been in reported in case of specific reactions with Estrace in a continuous regimen. In case of patients having impaired liver function and history of cholestatic jaundice Estrace may be poorly metabolized so precaution needs to be taken. In case of patients having hypothyroidism Estrace doses needs to be increased and maintained properly. The thyroid should be monitored properly and proper precaution needs to be taken. Estrace may cause fluid retention and it could affect factor like asthma, epilepsy and cardiac or renal dysfunction. Smoking is strictly avoided when consuming estradiol.

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